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Caspase-8 (T341) polyclonal antibody

货号: AP0358
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :AP0358
Product Name :Caspase-8 (T341) polyclonal antibody
Swiss-Prot :Q14790
Host :Rabbit
Reactivity :Human
Applications :WB
Application_all :WB: 1:500~1:1000
Background :Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Caspase-8 (T341) polyclonal antibody detects endogenous levels of Caspase-8 protein.
Note :~ 55 kDa
Pathway :For research use only, not for use in diagnostic procedure.
Alternative Name :MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Caspase 8.
Conjugate :Unconjugated
Modification :Unmodified
Western blot analysis of Caspase 8 expression in HEK293T (A), PC3 (B), Hela (C) whole cell lysates.
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关注我们

400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com