产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

PE mouse anti-human CD28 monoclonal antibody

货号: MB8503P

价格：￥

货期：现货（1-2个工作日）

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB8503P

Product Name :PE mouse anti-human CD28 monoclonal antibody

Swiss-Prot :P10747

Host :Mouse

Reactivity :Human

Applications :FC

Application_all :FC:5ul per test

Background :CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive (expression is independent of environmental factors).CD28 is the only B7 receptor constitutively expressed on naive T cells. Association of the TCR of a naive T cell with MHC:antigen complex without CD28:B7 interaction results in a T cell that is anergic.

Product :Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :Protein A affinity purified

Storage&Stability :Store at 4°C . Avoid freezed.

Specificity :This antibody detects Extracellular domain of human CD28.

Note :For research use only, not for use in diagnostic procedure.

Conjugate :Unconjugated

Modification :Unmodification

Flow cytometry analysis of human monocytes.