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EGFR mutant monoclonal antibody

货号: MB23526

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB23526

Product Name :EGFR mutant monoclonal antibody

Swiss-Prot :P00533

Host :Mouse

Reactivity :Human

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. <br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :175kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ERBB; HER1; mENA; ERBB1; PIG61

Immunogen :Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using EGFR mutant mouse mAb against SPC-A-1 (1), A549 (2), HepG2 (3) and MCF-7 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using EGFR mutant mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）