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WHSC2 monoclonal antibody

货号: MB23515

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23515

Product Name :WHSC2 monoclonal antibody

Swiss-Prot :Q9H3P2

Host :Mouse

Reactivity :Human,Rat

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. <br /><br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :57.3kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NELFA; NELF-A; P/OKcl.15

Immunogen :Purified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis usingwsC2 mouse mAb against Jurkat(1), HeLa (2), HEK293 (3), 4549 (51SPC-A-1 (6) cell lysate, and Rat brain4) fissue lysate.

Immunohistochemical analysis of oaraffn-embedded colon cancer tissues using WHSC2 mouse mAb with DAB staining

Immunofluorescence analysis of Hela calls using WHSC2 mouse mAb (green). Blue: DAA05 fuorescentDNA dye.

Fow cytometric analysis ofHEK293 cells using WHSC2 mouse mAb (green) and negative contro(purple).