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IRF3 monoclonal antibody

货号: MB23437

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23437

Product Name :IRF3 monoclonal antibody

Swiss-Prot :Q14653

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :47.2kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IIAE7

Immunogen :Purified recombinant fragment of human IRF3 (AA: 1-150) expressed in HEK293-6e cells supernatant.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using IRF3 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using IRF3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)