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SOCS3 monoclonal antibody

货号: MB23304

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23304

Product Name :SOCS3 monoclonal antibody

Swiss-Prot :O14543

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :24.8KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3

Immunogen :Purified recombinant fragment of human SOCS3 (AA: full(1-225)) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using SOCS3 mouse mAb against Hela cell lysate.

Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using SOCS3 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using SOCS3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)