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IGF1R monoclonal antibody

货号: MB23083

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB23083

Product Name :IGF1R monoclonal antibody

Swiss-Prot :P08069

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :154.8kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IGFR; CD221; IGFIR; JTK13

Immunogen :Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using IGF1R mouse mAb against NIH3T3 (1), cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）