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MDM2 monoclonal antibody

货号: MB22916

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB22916

Product Name :MDM2 monoclonal antibody

Swiss-Prot :Q00987

Host :Mouse

Reactivity :Human

Applications :IHC,FCM

Application_all :IHC:1/200-1/1000 FC:1/200-1/400

Background :This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :55.2kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HDMX; LSKB; hdm2; ACTFS

Immunogen :Purified recombinant fragment of human MDM2 (AA: 26-169) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using MDM2 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）