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ZAP70 monoclonal antibody

货号: MB22882

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB22882

Product Name :ZAP70 monoclonal antibody

Swiss-Prot :P43403

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :69.9kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70

Immunogen :Purified recombinant fragment of human ZAP70 (AA: 169-390) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ZAP70 mouse mAb against MLOT4 (1) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）