产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

COL1A2 monoclonal antibody

货号: MB22876

价格：￥ 1200

货期：现货（1-2个工作日）

25ug 50ug 100ug 200ug

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB22876

Product Name :COL1A2 monoclonal antibody

Swiss-Prot :P08123

Host :Mouse

Reactivity :Human,Mouse,Rat,Monkey

Applications :WB,IF,FCM

Application_all :WB:1/500-1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :129kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :OI4; EDSCV; EDSARTH2

Immunogen :Purified recombinant fragment of human COL1A2 (AA: 23-79) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using THY1 mouse mAb against NIH/3T3 cell lysate.

Immunofluorescence analysis of Hela cells using COL1A2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)