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NAGR1 monoclonal antibody

货号: MB22779

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22779

Product Name :NAGR1 monoclonal antibody

Swiss-Prot :P52272

Host :Mouse

Reactivity :Human,Mouse,Rat

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/500 FC:1/200 - 1/400

Background :This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :77.5kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HNRNPM; CEAR; HNRPM; HTGR1; HNRPM4; HNRNPM4; hnRNP M

Immunogen :Purified recombinant fragment of human NAGR1 (AA: 17-161) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using NAGR1 mouse mAb against U251 (1), PC-12 (2), HepG2 (3), A549 (4), HEK293 (5), NIH/3T3 (6), and Hela (7) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using NAGR1 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using NAGR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using NAGR1 mouse mAb (green) and negative control (red).