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RBBP7 monoclonal antibody

货号: MB22758

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :MB22758

Product Name :RBBP7 monoclonal antibody

Swiss-Prot :Q16576

Host :Mouse

Reactivity :Human,Mouse,Rat

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/500 FC:1/200 - 1/400

Background :This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :47.8kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RbAp46

Immunogen :Purified recombinant fragment of human RBBP7 (AA: 1-200) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using RBBP7 mouse mAb against Jurkat (1), HepG2 (2), F9 (3), C6 (4), LNCAP (5), HL-60 (6), Hela (7), and SH-SY5Y (8) cell lysate.

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using RBBP7 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using RBBP7 mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Flow cytometric analysis of Hela cells using RBBP7 mouse mAb (green) and negative control (red).