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RUNX3 monoclonal antibody

货号: MB22339

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22339

Product Name :RUNX3 monoclonal antibody

Swiss-Prot :Q13761

Host :Mouse

Reactivity :Human

Applications :IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/50 - 1/250 FC:1/200 - 1/400

Background :This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :44.4kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AML2; CBFA3; PEBP2aC

Immunogen :Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using RUNX3 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using RUNX3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)