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APEX1 monoclonal antibody

货号: MB22336

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22336

Product Name :APEX1 monoclonal antibody

Swiss-Prot :P27695

Host :Mouse

Reactivity :Human,Rat,Monkey

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :35.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :APE; APX; APE1; APEN; APEX; HAP1; REF1

Immunogen :Purified recombinant fragment of human APEX1 (AA: 219-318) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using APEX1 mouse mAb against Hela (1), Jurkat (2), SW480 (3), A431 (4), HepG2 (5), NIH/3T3 (6), and PC-12 (7) cell lysate.

Immunohistochemical analysis of paraffin-embedded human breast cancer tissues using APEX1 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）