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Phospho-4E-BP1 (Ser65) monoclonal antibody

货号: MB22311

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22311

Product Name :Phospho-4E-BP1 (Ser65) monoclonal antibody

Swiss-Prot :Q13541

Host :Mouse

Reactivity :Human

Applications :IHC,FCM

Application_all :IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :12.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EIF4EBP1; BP-1; 4EBP1; 4E-BP1; PHAS-I

Immunogen :Synthesized peptide of human Phospho-4E-BP1 (Ser65).

Conjugate :Unconjugated

Modification :Phosphorylated

Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using Phospho-4E-BP1 (Ser65) mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）