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ATF4 monoclonal antibody

货号: MB22298

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22298

Product Name :ATF4 monoclonal antibody

Swiss-Prot :P18848

Host :Mouse

Reactivity :Human

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. <br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :38.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CREB2; TXREB; CREB-2; TAXREB67

Immunogen :Purified recombinant fragment of human ATF4 (AA: 212-351) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ATF4 mouse mAb against K562 (1), A431 (2), Hela (3), HEK293 (4), and Ramos (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human breast cancer tissues using ATF4 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）