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P2RX7 monoclonal antibody

货号: MB22267

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB22267

Product Name :P2RX7 monoclonal antibody

Swiss-Prot :Q99572

Host :Mouse

Reactivity :Human,Mouse,Rabbit

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :68.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :P2X7

Immunogen :Purified recombinant fragment of human P2RX7 (AA: 226-452) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using P2RX7 mouse mAb against A431 (1), U251 (2), Hela (3), U937 (4), and HepG2 (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using P2RX7 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）