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LMNB2 monoclonal antibody

货号: MB22144

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22144

Product Name :LMNB2 monoclonal antibody

Swiss-Prot :Q03252

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :67.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LMN2; LAMB2

Immunogen :Purified recombinant fragment of human LMNB2 (AA: 401-600) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using LMNB2 mouse mAb against PC-3 (1), LNcap (2), Jurkat (3), and HCT116 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using LMNB2 mouse mAb with DAB staining.

Immunofluorescence analysis of GC-7901 cells using LMNB2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using LMNB2 mouse mAb (green) and negative control (red).