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CDH11 monoclonal antibody

货号: MB22140

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22140

Product Name :CDH11 monoclonal antibody

Swiss-Prot :P55287

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. <br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :88kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :OB; CAD11; CDHOB; OSF-4

Immunogen :Purified recombinant fragment of human CDH11 (AA: 468-617) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CDH11 mouse mAb against MCF-7 (1), Jurkat (2), and HEK293 (3) cell lysate.

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CDH11 mouse mAb with DAB staining.

Immunofluorescence analysis of HL-7702 cells using CDH11 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using CDH11 mouse mAb (green) and negative control (red).