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SNAI2 monoclonal antibody

货号: MB21900

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21900

Product Name :SNAI2 monoclonal antibody

Swiss-Prot :O43623

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :30kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SLUG; WS2D; SLUGH1; SNAIL2

Immunogen :Purified recombinant fragment of human SNAI2 (AA: 100-200) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using SNAI2 mouse mAb against MCF-7 cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using SNAI2 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using SNAI2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of MCF-7 cells using SNAI2 mouse mAb (green) and negative control (red).