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XRCC6 monoclonal antibody

货号: MB21861

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21861

Product Name :XRCC6 monoclonal antibody

Swiss-Prot :P12956

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :69.8kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ML8; KU70; TLAA; CTC75; CTCBF; G22P1

Immunogen :Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using XRCC6 mouse mAb against Hela (1), PC-2 (2), A549 (3), A431 (4), HepG2 (5), K562 (6) cell lysate.

Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using XRCC6 mouse mAb with DAB staining.

Immunofluorescence analysis of MCF-7 cells using XRCC6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of A431 cells using XRCC6 mouse mAb (green) and negative control (red).