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SDC1 monoclonal antibody

货号: MB21840

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21840

Product Name :SDC1 monoclonal antibody

Swiss-Prot :P18827

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IF,FCM

Application_all :WB:1/500 - 1/2000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :32.5kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SDC; CD138; SYND1; syndecan

Immunogen :Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using SDC1 mouse mAb against Hela (1), MCF-7 (2), HepG2 (3), T47D (4), Jurkat (5), NIH/3T3 (6) cell lysate.

Immunofluorescence analysis of HepG2 cells using SDC1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)