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MMP2 monoclonal antibody

货号: MB21687

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB21687

Product Name :MMP2 monoclonal antibody

Swiss-Prot :P08253

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. <br /><br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :73.8kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CLG4; MONA; CLG4A; TBE-1; MMP-II

Immunogen :Purified recombinant fragment of human MMP2 (AA: 242-396) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using MMP2 mouse mAb against A431 (1) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）