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RUNX3 monoclonal antibody

货号: MB21657

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21657

Product Name :RUNX3 monoclonal antibody

Swiss-Prot :Q13761

Host :Mouse

Reactivity :Human,Mouse

Applications :IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :44.4kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070

Immunogen :Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using RUNX3 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）