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VAV1 monoclonal antibody

货号: MB21640

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB21640

Product Name :VAV1 monoclonal antibody

Swiss-Prot :P15498

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/250 FC:1/200 - 1/400

Background :The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :98.3kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VAV

Immunogen :Purified recombinant fragment of human VAV1 (AA: 121-324) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using VAV1 mouse mAb against Jurkat (1) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）