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HEXA monoclonal antibody

货号: MB21594

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21594

Product Name :HEXA monoclonal antibody

Swiss-Prot :P06865

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :60.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TSD

Immunogen :Purified recombinant fragment of human HEXA expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using HEXA mouse mAb against L1210 (1), and HL7702 (2) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）