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CDK9 monoclonal antibody

货号: MB21471

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21471

Product Name :CDK9 monoclonal antibody

Swiss-Prot :P50750

Host :Mouse

Reactivity :Human

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :43kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TAK; C-2k; CTK1; CDC2L4; PITALRE

Immunogen :Purified recombinant fragment of human CDK9 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CDK9 mouse mAb against Jurkat (1), A431 (2) and HEK293 (3) cell lysate.

Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues (left) and rectum cancer tissues (right) using CDK9 mouse mAb with DAB staining.