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MSI2 monoclonal antibody

货号: MB21442

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21442

Product Name :MSI2 monoclonal antibody

Swiss-Prot :Q96DH6

Host :Mouse

Reactivity :Human

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :35kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MSI2H; MGC3245; FLJ36569; MSI2

Immunogen :Purified recombinant fragment of human MSI2 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using MSI2 mouse mAb against NTERA-2 (1), SW620 (2) and T47D (3) cell lysate.

Immunohistochemical analysis of paraffin-embedded human ovarian cancer (left) and cerebellum tissues (right) using MSI2 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）