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AURKA monoclonal antibody

货号: MB21427

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21427

Product Name :AURKA monoclonal antibody

Swiss-Prot :O14965

Host :Mouse

Reactivity :Human,Rat,Monkey

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :48kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; AURORA2; MGC34538; AURKA

Immunogen :Purified recombinant fragment of human AURKA expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using AURKA mouse mAb against HEK293 (1), Sw620 (2), MCF-7 (3), Jurkat (4), Hela (5), HepG2 (6), Cos7 (7) and PC-12 (8) cell lysate.

Immunohistochemical analysis of paraffin-embedded human ovarian cancer (left) and lung cancer (right) using AURKA mouse mAb with DAB staining.