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KDM3A monoclonal antibody

货号: MB21402

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21402

Product Name :KDM3A monoclonal antibody

Swiss-Prot :Q9Y4C1

Host :Mouse

Reactivity :Human

Applications :WB,IF

Application_all :WB:1/500 - 1/2000 IF:1/200 - 1/1000

Background :This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and alpha-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :147kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A; KIAA0742; DKFZp686A24246; DKFZp686P07111; KDM3A

Immunogen :Purified recombinant fragment of human KDM3A expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using KDM3A mouse mAb against Hela (1) and HepG2 (2) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）