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PAX8 monoclonal antibody

货号: MB21387

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21387

Product Name :PAX8 monoclonal antibody

Swiss-Prot :Q06710

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.Tissue specificity: Expressed in the excretory system, thyroid gland and Wilms tumors.ABCAM: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :60kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PAX8

Immunogen :Purified recombinant fragment of human PAX8 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using PAX8 mouse mAb against Hela (1)HEK293 (2) and Raji (3) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）