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KI67 monoclonal antibody

货号: MB21372

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21372

Product Name :KI67 monoclonal antibody

Swiss-Prot :P46013

Host :Mouse

Reactivity :Human,Mouse,Rat,Rabbit,Monkey

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :Ki67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :358kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIA; Ki-67; MKI67

Immunogen :Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using KI67 mouse mAb against Hela (1), MCF-7 (2) and Raji (3) cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and rectal cancer (right) using KI67 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）