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ESR1 monoclonal antibody

货号: MB21371

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21371

Product Name :ESR1 monoclonal antibody

Swiss-Prot :P03372

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000

Background :This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :66kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ER; ESR; Era; ESRA; NR3A1; DKFZp686N23123; ESR1

Immunogen :Purified recombinant fragment of human ESR1 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ESR1 mouse mAb against MCF-7 (1), T47D (2) and SKBR3 (3) cell lysate.

Immunohistochemical analysis of paraffin-embedded human mammary cancer tissues using ESR1 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using ESR1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

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