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NME1 monoclonal antibody

货号: MB21334

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21334

Product Name :NME1 monoclonal antibody

Swiss-Prot :P15531

Host :Mouse

Reactivity :Human

Applications :IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :non-metastatic cells 1,protein,with a nm23 nucleoside diphosphate kinase gene family,involved in the phosphorylation of nucleoside diphosphates,with a reduced expression in tumor progression to the metastatic phenotype,mutated in agressive neuroblastoma,expressed in lung carcinoma cell lines not in normal lung,pyrimidine biosynthetic pathway. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Has tumor metastasis-suppressive capacity.Tissue specificity: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :17kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NB; AWD; NBS; GAAD; NM23; NDPKA; NDPK-A; NM23-H1; NME1

Immunogen :Purified recombinant fragment of human NME1 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human Placenta tissues using anti-NME1 mouse mAb

Immunofluorescence analysis of Hela cells using NME1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.