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CHD3 monoclonal antibody

货号: MB21279

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21279

Product Name :CHD3 monoclonal antibody

Swiss-Prot :Q12873

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :226kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ZFH; Mi-2a; Mi2-ALPHA; CHD3

Immunogen :Purified recombinant fragment of human CHD3 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CHD3 mouse mAb against Hela (1), K562 (2), Jurkat (3), NTERA-2 (4), HEK293 (5), Raji (6) cell lysate and mouse brain (7) tissue lysate.

Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using CHD3 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using CHD3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Flow cytometric analysis of K562 cells using CHD3 mouse mAb (green) and negative control (purple).