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KRT15 monoclonal antibody

货号: MB21270

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21270

Product Name :KRT15 monoclonal antibody

Swiss-Prot :P19012

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :49kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :K15; CK15; K1CO; KRT1

Immunogen :Purified recombinant fragment of KRT15 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using KRT15 mouse mAb against A431 cell lysate.

Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using KRT15 mouse mAb

Immunofluorescence analysis of HepG2(left) and PACN-1 (right) cells using KRT15 mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

Flow cytometric analysis of PACN-1 cells using KRT15 mouse mAb (green) and negative control (purple).