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NF-κB p65 monoclonal antibody

货号: MB21267

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21267

Product Name :NF-κB p65 monoclonal antibody

Swiss-Prot :Q04206

Host :Mouse

Reactivity :Human,Mouse,Rat,Rabbit,Monkey

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/100 - 1/500

Background :NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :65kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NFkappaB p65; p65; NFKB3; RELA

Immunogen :Purified recombinant fragment of human NF-κB p65 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using NF-κB p65 mouse mAb against Jurkat (1), K562 (2) and NIH/3T3 (3) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）