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JAK3 monoclonal antibody

货号: MB21265

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21265

Product Name :JAK3 monoclonal antibody

Swiss-Prot :P52333

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IF,FCM

Application_all :WB:1/500 - 1/2000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :125kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :JAKL; LJAK

Immunogen :Purified recombinant fragment of human JAK3 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using JAK3 mouse mAb against Jurkat cell lysate (1).

Confocal Immunofluorescence analysis of Hela (left) and HepG2 (right) cells using JAK3 mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.