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NTRK3 monoclonal antibody

货号: MB21251

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB21251

Product Name :NTRK3 monoclonal antibody

Swiss-Prot :Q16288

Host :Mouse

Reactivity :Human

Applications :WB,IHC

Application_all :IHC:1/200 - 1/1000

Background :NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :94kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TRKC; gp145(trkC)

Immunogen :Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using NTRK3 mouse mAb against extracellular domain of human NTRK3 (aa32-429).

Immunohistochemical analysis of paraffin-embedded human lymph node using NTRK3 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）