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ROR1 monoclonal antibody

货号: MB21248

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21248

Product Name :ROR1 monoclonal antibody

Swiss-Prot :Q01973

Host :Mouse

Reactivity :Human

Applications :WB,IF

Application_all :IF:1/200 - 1/1000

Background :ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :101kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ROR1

Immunogen :Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ROR1 mouse mAb against extracellular domain of human ROR1 (aa30-423).

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）