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PAK2 monoclonal antibody

货号: MB21236

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21236

Product Name :PAK2 monoclonal antibody

Swiss-Prot :Q13177

Host :Mouse

Reactivity :Human,Monkey

Applications :WB,IHC,IF

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000

Background :PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :61kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PAK65; PAKgamma

Immunogen :Purified recombinant fragment of PAK2 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using PAK2 mouse mAb against Hela (1), Jurkat (2), A549 (3), HEK293 (4) and K562 (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and gastric cancer (right) using PAK2 mouse mAb with DAB staining.

Confocal Immunofluorescence analysis of Hela cells using PAK2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

免疫沉淀（IP）