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ETV4 monoclonal antibody

货号: MB21168

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21168

Product Name :ETV4 monoclonal antibody

Swiss-Prot :P43268

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :ETV4: ets variant gene 4 (E1A enhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-a. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :54kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HGK; NIK; PEA3

Immunogen :Purified recombinant fragment of human ETV4 (aa50-109) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ETV4 mouse mAb against K562 cell lysate (1).

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）