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PTK6 monoclonal antibody

货号: MB21102

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB21102

Product Name :PTK6 monoclonal antibody

Swiss-Prot :Q13882

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :PTK6 (protein tyrosine kinase 6, BRK or FLJ42088), with 451-amino acid protein (about 52kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :52kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BRK; FLJ42088

Immunogen :Purified recombinant fragment of human PTK6 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using PTK6 mouse mAb against Hela (1), A549 (2) and MCF-7 (3) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）