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INHA (Inhibin alpha) monoclonal antibody

货号: MB21091

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21091

Product Name :INHA (Inhibin alpha) monoclonal antibody

Swiss-Prot :P05111

Host :Mouse

Reactivity :Human

Applications :IHC,IF

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000

Background :INHA (A-inhibin subunit precursor, inhibin alpha subunit ), also called inhibin (alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :40kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :INHA; inhibin, alpha

Immunogen :Purified recombinant fragment of human INHA expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human lymphoid (A), ovary tumor (B) and testicle tumor (C) tissues using INHA mouse mAb with DAB staining.