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Lck monoclonal antibody

货号: MB21074

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB21074

Product Name :Lck monoclonal antibody

Swiss-Prot :P06239

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :Lck (lymphocyte-specific protein tyrosine kinase), with 509-amino acid protein (about 56kDa), belongs to the Src non-receptor tyrosine kinases family. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is expressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. In addition, inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :56kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :YT16; p56lck; pp58lck

Immunogen :Purified recombinant fragment of human Lck expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using LCK mouse mAb against MOLT-4 (1), CCRF-CEM (2), CCRF-HSB-2 (3) and Jurkat (4) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）