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LSD1/AOF2 monoclonal antibody

货号: MB21061

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21061

Product Name :LSD1/AOF2 monoclonal antibody

Swiss-Prot :O60341

Host :Mouse

Reactivity :Human,Mouse,Monkey

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :93kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KDM1; LSD1; AOF2

Immunogen :Purified recombinant fragment of human LSD1 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using LSD1 mouse mAb against COS (1), Hela (2), NIH/3T3 (3), A549 (4) and Jurkat (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma (left) and kidney carcinoma (right), showing nuclear localization using LSD1 mouse mAb with DAB staining.