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LYVE1 polyclonal antibody

货号: BS90816

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS90816

Product Name :LYVE1 polyclonal antibody

Swiss-Prot :Q9Y5Y7

Host :Rabbit

Reactivity :Human

Applications :WB, IHC-P, IP

Application_all :WB:1:1,000 IHC-P:1:1000-1:10000 IP:1:20

Background :Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) is expressed on the cell surface as a protein that is reduced by glycosidase treatment. LYVE-1 is abundant in spleen, lymph node, heart, lung and fetal liver, and is less abundant in appendix, bone marrow, placenta, muscle and adult liver. Expression of LYVE-1 is largely restricted to endothelial cells lining lymphatic vessels and splenic sinusoidal endothelial cells. LYVE-1 binds to both soluble and immobilized hyaluronan (HA) with greater specificity than HCAM. Like HCAM, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike HCAM, the LYVE-1 molecule co-localizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. LYVE-1 is used as a marker to study tumor lymphangiogenesis, which is an important area of investigation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LYVE1 polyclonal antibody detects endogenous levels of LYVE1 protein.

BiowMW :55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HAR; XLKD1; LYVE-1; CRSBP-1

Immunogen :Recombinant fusion protein of human LYVE1.

Conjugate :Unconjugated

Modification :Unmodified

1上架，0下架 :1

限时特惠: 1是，0否 :1