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MMP1 polyclonal antibody

货号: BS66270

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS66270

Product Name :MMP1 polyclonal antibody

Swiss-Prot :P03956

Host :Rabbit

Reactivity :Human, Mouse, Rat, Monkey, Rabbit

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500

Background :This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MMP1 polyclonal antibody detects endogenous levels of MMP1 protein.

BiowMW :52KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MMP1.

Conjugate :Unconjugated

Modification :Unmodified

1上架，0下架 :1

限时特惠: 1是，0否 :1

Western blot analysis of MMP1 expression in HEK293T (A), Hela (B), A375 (C) whole cell lysates.

Immunohistochemical analysis of MMP1 staining in human lung cancer formalin fixed paraffin embedded tissue section.