Product Name :SAMD1 polyclonal antibody
Application_all :WB,1:500 - 1:1000
Background :Unmethylated CpG islands (CGIs)-binding protein which localizes to H3K4me3-decorated CGIs, where it acts as a transcriptional repressor. Tethers L3MBTL3 to chromatin and interacts with the KDM1A histone demethylase complex to modulate H3K4me2 and H3K4me3 levels at CGIs. Plays a role in atherogenesis by binding with LDL on cell surface and promoting LDL oxidation which leads to the formation of foam cell.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :SAMD1 polyclonal antibody detects endogenous levels of SAMD1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Atherin; Sterile alpha motif domain-containing protein 1; SAM domain-containing protein 1
Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SAMD1.
