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SLC7A11 Rabbit monoclonal antibody

货号: BS66263

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS66263

Product Name :SLC7A11 Rabbit monoclonal antibody

Swiss-Prot :Q9UPY5

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC, IP

Application_all :WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200|IP,1:10 - 1:50

Background :This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. xCT has a predicted molecular weight of 55 kDa; however it has a high number of hydrophobic residues which may affect the migration of the protein in SDS-PAGE. Endogenous monomeric xCT is expected to migrate at ~35 kDa and modified-xCT is expected to migrate at ~55 kDa (PMID: 17035536)

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SLC7A11 Rabbit monoclonal antibody detects endogenous levels of SLC7A11 protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT

Immunogen :KLH-conjugated synthetic peptide of human SLC7A11.

Conjugate :Unconjugated

Modification :Unmodified

1上架，0下架 :1

限时特惠: 1是，0否 :1

Western blot analysis of SLC7A11 expression in Jurkat (A), Hela (B), K562 (C), mouse liver (D), mouse muscle (E), rat liver (F), rat muscle (G) whole cell lysates.